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The Top Rated Anti Stress & Anxiety Supplements of 2021

Daniel Gold

Health Editor

Daniel holds a PhD in Cognitive Science from Harvard University specializing in Neuro Science. He has taught at seventeen universities in the USA and currently Advises Top Ranked Medical Schools and Hospitals. He has won many awards for his research in applied Cognitive Science and was featured on Medical News Today’s Top Medical Professionals list. Daniel is a Father of 4 Beautiful girls, a IronMan Athlete and UCLA Medical Centers Top Practitioner of the Year (2019)

How We Found the Best Supplements

117 Supplements

3 Experts
Consulted
5 Top Picks

Are you tired of feeling gut-wrenching worry, fear, trouble sleeping, fatigue or simply not feeling like yourself? Don’t worry, you’ve come to the right place.

In one medical study, researchers found that 79% of Americans overall – and 91% of those with severe anxiety – reported using supplements to manage their Anxiety Symptoms. And their results may startle you.

Anxiety is a condition that plagues millions all over the world. It comes in many different forms and affects a variety of people. Anxiety is your body’s natural response to stress, and can become a serious chronic condition. It can begin with bouts of panic attacks or as a result of a traumatizing situation from the past. It brings about feelings of apprehension or fear that can become debilitating.

Anti-anxiety supplements effectively ease symptoms of anxiety in many individuals, reducing that stressful rush of nerves in your system and promoting relaxation and a more positive outlook in life. But because anxiety is a generally difficult condition to understand, it’s no surprise that the industry is filled with confusing information and myths.

Here, we’ve provided you with fast tips and tricks on what to look for when searching for an effective anti-anxiety supplement. By knowing fact from fiction, you will be empowered to make a successful purchase.

 

Our Ranking System

This specialized ranking system follows a unique criteria and comprehensive process in which we measure the value of the products by carefully evaluating the ingredients, safety, efficacy, refund policies, and overall customer satisfaction. These factors, combined with the latest studies and clinical trials, makes it easy to choose the best products available in the market, saving you both time and money.

Unwanted Ingredients In A Stress & Anxiety Supplement

Refined Sugar

Consuming excessive amounts of sugar can cause chemical changes in your body. It can makes us feel good, and provides feelings of pleasure. However, these salutatory effects are all temporary. After all, what goes up must come down. When you have a come down from sugar it can result in a sugar hangover.

Caffeine

While it increases speed and efficiency, and temporarily elevates mood, in many people caffeine also triggers the release of the stress hormones cortisol, adrenaline, and beta adrenaline. The release of these hormones amplifies any already existing anxiety, elevating nervousness and bring on the jitters.

Food Additives

Dyes and artificial sweeteners are neurotoxins and can leave the neurons in a state of communication breakdown. This disrupts normal nervous system function. When this happens, typically due to an interference in neurotransmission, anxiety and other mood disturbances can occur.

Table of Contents

Guide To Stress & Anxiety Supplements

What Are Stress & Anxiety Supplements

Stress & Anxiety Supplement Benefits

What To Look For
What To Avoid

The Best Stress & Anxiety Supplements

A Good Stress/Anxiety Supplement Helps To:

Enhance Mood

Promote Focus and Alertness 

Eliminate Stress

Eliminate Anxiety

Relieve Panic Attacks

Boost Mental Energy 

Enhance Creativity 

Promote Healthy Blood Pressure

Fight Cognitive Decline 

Top 3 Criteria For A Quality Stress & Anxiety Supplement

We spent months researching Stress & Anxiety supplements and gathering user feedback. There are specific ingredients that, when present in a formula, help differentiate high-quality supplements from generic ones. Below are the three most essential ingredients to consider before deciding on which brand is best for your needs.

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#1 Doctor Approved

The only way to ensure you are getting the best is to make sure the supplement is backed by a Doctor. This is becuase there are many brands that claim their supplement is the best, but only the ones who can invest in proven results should make it into your diet.

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#2 Long Lasting

You need to ensure that the supplement you take is effective for at least 24 hours. This not only helps you save money, but it also helps you maintain optimal health.

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#3 Contains No Artifical Fillers

Many companies try to cut costs by putting fillers in their supplements. This reduces the value you get in each bottle. In addition, the effects of fillers with many primary ingredients are unknown. It is best for your health to avoid them.

4 Things To AVOID
When Buying A Nootropic Supplement

1. Formulas Lacking Essential Vitamins

The brain needs a steady supply of neuro-vitamins and nutrients so it can function properly. Avoid any formula which does not include a complex of B vitamins, vitamin C, vitamin E, magnesium, choline, and zinc.27-29

2. Not Backed By A Doctor

Creating an effective supplement requires a solid understanding of which ingredients to use and in what level of potency. Avoid a brand which is not supported by a credible doctor.

3. Insufficient Return Policy

A reputable supplement brand will demonstrate they have faith in their product by offering a 100% money-back guarantee policy. Some try to complicate their refund policies by placing limitations on what kind of returns they will take. Avoid any brand that does not have at minimum a no questions asked 90-day money-back guarantee.

4. Depending on Amazon Reviews

Research showed that in March 2019, there were 1.8 million new unverified reviews, with an average of 99.6% of them being 5-star reviews. Most of these reviews are from people paid to write them. These fake reviews inflate the number and overall star rating of a product. When deciding on a supplement that can impact your health, don’t rely on Amazon reviews as they can be extremely misleading.

2021’s Top Five Stress & Anxiety Supplements

Our review encompassed 117 different supplements, putting each through our rigorous Medical Pro Expert assessment process. To determine 2021’s Top 5 Stress & Anxiety Supplements, we look for predicted effectiveness, supporting studies, safety, pricing, return policy, and overall customer satisfaction.

#1 Summit Labs RegenMax

PROS

41 Vitamins and Nutrients

Contains Phosphatidylserine, Bacopa Monnieri, and Huperzine A

Includes the nutrient Choline

Endorsed by a Doctor

Natural Capsules, Non-GMO, Gluten, Lactose, and Antibiotic Free, No artificial ingredients or fillers

Verified 90-day 100% money-back return policy

CONS

Often out of stock due to high demand

Why We Chose It

Summit Lab’s RegenMax is MedicalProExperts top choice. This formula contains a potent dose of 41 different vitamins, minerals, and nutrients, including all three of the essential ingredients Phosphatidylserine, Bacopa Monnieri, and Huperzine A.

RegenMax also includes the nutrient Choline, needed to make the neurotransmitter acetylcholine, which plays a crucial role in Stress & Anxiety relief. We were impressed that this formula included a robust Vitamin B complex and a large variety of other essential vitamins and nutrients that studies have demonstrated play a protective role against cognitive decline.

We were able to verify that Summit Lab’s formula does not contain any synthetic fillers or artificial ingredients and is non-GMO. Summit Labs backs its products with a no-questions-asked, 90-day money-back guarantee and is one of the few brands to be endorsed by a board-certified doctor. We also like that they offer customers discounts on bundles.

Click on the Link BELOW to read a Full Review

*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.
READ FULL REVIEW HERE
#2 Qualia Mind

PROS

28 Vitamins and Nutrients
Contains All 3 Essential Ingredients

Vegetarian Capsules, Non-GMO, and Vegan

Endorsed by a Doctor

CONS

Very expensive monthly price
Must take 7 pills per dose
Mixed consumer reviews
Return policy limited to first time purchase only

Why We Chose It

Qualia Mind is a popular brand thanks in part to their heavy web advertising. The product contains a robust array of 28 different vitamins and nutrients, including all three of our top recommended ingredients. However, Qualia has about 30% fewer ingredients than the top-ranked brand on our list, yet it is more than three times the price for a 30-day supply. Qualia enrolls customers in a monthly auto-ship program, which has an introductory price of $69.50 for the first month and $119.00 for each month after that. If you are not a fan of having your card automatically charged each month, then the price for a 30-day supply is a jaw-dropping $139.00. Qualia Mind is endorsed by a physician and is GMO and gluten-free. However, consumers have provided mixed reviews on how well the product works. The company offers a limited 100-day money-back guarantee, as it only applies to your very first order.
*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.
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#3 Genius Consciousness

PROS

Contains Phosphatidylserine
Contains Huperzine A
Non-GMO, Soy and Gluten-Free

CONS

Does not contain Bacopa Monnieri
Does not come in capsule form
Does not contain essential vitamins and nutrients
Conflicting return policies

Why We Chose It

Genius Consciousness by The Genius Brand is a popular product that contains ten different ingredients, including two out of the three critical ingredients. It is missing the inclusion of the essential Bacopa Monnieri. While we liked that the product contains Lion’s Mane Mushroom, which has a variety of health benefits, we were disappointed to see a lack of essential vitamins and nutrients, such as a B complex. A drawback of this product is that it does not come in a convenient capsule but rather a watermelon flavored powder, which some may find a hassle to mix with water each day. Consumers have also reported mixed reviews on the taste. The return policy for Genius Consciousness is unclear as their website product page indicates a 30-day return policy, but elsewhere on the site indicates a 90-day return period.
*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.
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#4 Neuriva

PROS

Contains Phosphatidylserine
Caffeine and GMO-Free

CONS

Does not contain Bacopa Monnieri or Huperzine A
User complaints related to headaches, sleep issues, and allergic reactions
Very expensive for minimal ingredients
Contains allergen Soy Lecithin
Limited 30-day return policy

Why We Chose It

Neuriva by Schiff Vitamins is a relatively new product intended to improve brain performance. Neuriva comes in “Original” and “Plus” formulas, containing Phosphatidylserine and Coffee Fruit Extract. The “Plus” formula adds vitamins B6, B12, and B9. However, neither version contains our top-ranking ingredients Bacopa Monnieri and Huperzine A, and the vital nutrient Choline. Neuriva’s key ingredient, Coffee Fruit Extract (Coffee arabica), has only one study to its credit, suggesting it improves cognitive function. We prefer to see ingredients that have more substantial evidence to support memory and focus claims.

We were happy to see that Neuriva is both caffeine and GMO-free. However, allergic reactions have been reported since Neuriva contains soy lecithin and rice. Users have also reported having sleeping issues when taking this product. Neuriva provides a 30-day refund period, but that is only for unopened bottles, which is not much of a guarantee if you find that you’re unhappy with the results.

*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.
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#5 Prevagen

PROS

Contains Synthetic Apoaequorin

CONS

Doesn’t contain Phosphatidylserine, Bacopa Monnieri, or Huperzine A
Does not contain essential vitamins and nutrients
Significant FTC and FDA Legal Issues related to False Claims
Very Expensive considering the lack of proven ingredients
Limited 45-day Return Policy

Why We Chose It

Prevagen by Quincy Biosciences is a product made famous thanks to their massive spending on television advertising. In recent years, the brand has also become infamous for its extensive legal issues related to false claims. This formula, sold in both a capsule and chewable form and a regular and extra strength version, contains apoaequorin, a protein derived from jellyfish. Through their single clinical study, the manufacturer claims that Prevagen helps improve cognitive function and memory by replacing proteins in the brain that are lost during the aging process.

Unfortunately, it appears that not everyone agrees with this theory. In 2017 the Federal Trade Commission (FTC) and the New York Attorney General sued Quincy Biosciences for making false claims. The primary issue asserted by the FTC is that proteins consumed orally, as in a pill or chewable tablet, go straight to the stomach where they get broken down into amino acids. In the form of amino acids, they can’t travel to the brain and then re-convert into a protein to replace any proteins lost due to aging. The story does not make sense from a science perspective. The FTC also charged Prevagen with making false claims stating the company’s own clinical study in actuality showed no statistically significant improvement in memory and cognitive function between those given Prevagen and those given a placebo.

In a non-related matter, the FDA has opened a case stating that Prevagen did not warn its users that seizures and strokes were some of the many adverse side effects of taking Prevagen.

While some users have reported benefits from taking Prevagen, we recommend avoiding the marketing hype and possible side effects. Choose a formula with a variety of vitamins, minerals, and neuro-nutrients such as Phosphatidylserine, Bacopa Monnieri, and Huperzine A, shown in studies over the years to help support memory and cognitive health.

*Results are based on user-generated experiences with these products, and individual results may vary. Please refer to the manufacturer’s product website for detailed information.
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© Copyright 2019 – 2021
* Results will differ for each individual, depending on existing health factors, lifestyle and physical condition. The information contained on this site is for informational purposes only and is not a substitute for medical advice provided by your doctor or physician. The information, we provide should not be used for diagnosis, treatment or prevention of any disease. Testimonials and results contained are reflective of the typical examples consumers experienced and may not be an implication of future results for you. These statements have not been evaluated by the Food and Drug Administration. As an Amazon Associate we earn from qualifying purchases.